業績 PUBLICATIONS
原著論文 Paper 2014年以前 Before2014
2015年以降 After 2015
2007年以前 Before 2007
2014年
88) Y. Yamagishi, T. Masuda, M. Matsusaki, M. Akashi, U. Yokoyama, F. Arai,
“Microfluidic perfusion culture system for multilayer artery tissue models”, Biomicrofluidics, 8, 064113/1-064113/10 (2014).
87) Akihiro Nishiguchi, Michiya Matsusaki, Mitsuru Akashi, “Cell-Cell Crosslinking by Bio-Molecular Recognition of Heparin-Based Layer-by-Layer
Nanofilms”. Macromol. Biosci., 15, 312-317 (2015). Elected as a front cover
86) Paninee Chetprayoon, Fumiaki Shima, Michiya Matsusaki, Takami Akagi,
Mitsuru Akashi, “Sustainable Release of Paclitaxel from Biodegradable Poly(gamma-glutamic
acid) Nanoparticles for Treatment of Atherosclerosis”, Chem. Lett., 43, 1767-1769 (2014).

85) A. Matsuzawa, M. Matsusaki, M. Akashi, “Construction of Three-Dimensional Liver Tissue Models by a Cell Accumulation
Technique and Metabolic Function Maintenance in a Long-Term Culture without
Medium Change”, J. Biomed. Mater. Res. Part A, 103A, 1554-1564 (2015)

84) C. Liu, M. Matsusaki, M. Akashi, “The Construction of Cell-Density Controlled Three-Dimensional Tissues
by Coating Micrometer-Sized Collagen Fiber Matrices on Single Cell Surfaces”, RSC Adv., 4, 46141 (2014).

83) S. H. Ryu, Y. Hashizume, M. Mishima, R. Kawamura, M. Tamura, H. Matsui,
M. Matsusaki, M. Akashi, C. Nakamura, “Measurement of Cell Adhesion Force by Vertical Forcible Detachment Using
an Arrowhead Nanoneedle and AFM”, Biochem. Biophys. Res. Commun., 451, 107-111 (2014).

82) D. J. Curtis, A. Sood, T. J. Phillips, V. H.L. Leinster, A. Nishiguchi,
C. Coyle, L. Lacharme-Lora, O. Beaumont, H. Kemp, R. Goodall, L. Cornes,
M. Giugliano, R. Barone, M. Matsusaki, M. Akashi, H. Y. Tanaka, M. Kano,
J. McGarvey, N. D. Halemani, K. Simon, R. Keehan, W. Ind, T. Masters, S.
Grant, S. Athwal, G. Collett, D. Tannetta, I. L. Sargent, E. Scull-Brown,
X. Liu, K. Aquilina, N. Cohen, J. D. Lane, M. Thoresen, J. Hanley, A. Randall,
C. Patrick Case, “Secretions from placenta, after hypoxia/reoxygenation, can damage developing
neurones of brain under experimental conditions”, Exp. Neurol. 261, 386-395 (2014).

81) Y. Asano, A. Nishiguchi, D. Okano, T. Fujita, E. Saito, M. Matsusaki,
M. Akashi, H. Shimoda, “Ultrastructure of Blood and Lymphatic Vascular Networks in Three-dimensional
Cultured Tissues Fabricated by ECM nanofilm-based Cell Accumulation Technique”, Microscopy, 63, 219-226 (2014).

80) Akihiro Nishiguchi, Michiya Matsusaki, Yoshiya Asano, Hiroshi Shimoda,
Mitsuru Akashi, “Effects of Angiogenic Factors and 3D-Microenvironments on Vascularization within Sandwich Cultures”, Biomaterials, 35, 4739-4748 (2014).

79) R. Ishiwata, U. Yokoyama, Y. Ichikawa, M. Umemura, T. Fujita, S. Minamisawa,
M. Matsusaki, M. Akashi, Y. Ishikawa, “Three-dimensional Multilayers of Smooth Muscle Cells in a New Experimental
Model for Studies of Vascular Elastic Fiber Formation Studies”, Atherosclerosis, 233, 590-600 (2014).

78) Masahiro Matsumoto, Michiya Matsusaki, Mitsuru Akashi, “Preparation of Biodegradable Peptide Nanospheres with Hetero PEG Brush
Surfaces”, Macromol. Biosci., 42, 142-150 (2014).

2013年
77) Atsushi Matsuzawa, Michiya Matsusaki, Mitsuru Akashi, “Effectiveness of Nanometer-sized Extracellular Matrix Layer-by-Layer Films
Coated on Cell Membranes in Protecting the Cells from Physical Stress”, Langmuir, 29, 7362-7368 (2013).

76) Sho Shinohara, Takanori Kihara, Shinji Sakai, Michiya Matsusaki, Mitsuru
Akashi, Masahito Taya, Jun Miyake, “Fabrication of in vitro three-dimensional multilayered blood vessel model
using human endothelial and smooth muscle cells and high-strength PEG hydrogel”, J. Biosci. Bioeng., 116, 231-234 (2013).

75) Masahiro Matsumoto, Michiya Matsusaki, Mitsuru Akashi, ”Safe Control of Construction-Deconstruction of High-Density PEG Brushes
on the Surface of Peptide Nanospheres by Thermally-Induced Shrinkage of
PEG-SS-PEG”, Chem. Lett., 42, 344-346 (2013).

74) Michiya Matsusaki, Kayo Sakaue, Koji Kadowaki, Mitsuru Akashi, “Three-dimensional Human Tissue Chips Fabricated by Rapid and Automatic Inkjet Cell Printing”, Adv. Healthcare Mater., 2, 534-539 (2013). Elected as a frontispiece.

73) Hiroaki Yoshida, Michiya Matsusaki, and Mitsuru Akashi, “Multilayered Blood Capillary Analogs in Biodegradable Hydrogels for In
Vitro Drug Permeability Assay”, Adv. Funct. Mater., 23, 1736-1742 (2013). Elected as an inside cover.

2012年
72) Koji Kadowaki, Michiya Matsusaki, Mitsuru Akashi, “Control of Cellular Inflammation by Layer-by-Layer Nanofilms through Different
Driving Forces”, Chem. Lett., 41, 523 (2012).

71) Amornrart. Lertworasirikul, Nu-om Choothong, Hiroaki Yoshida, Michiya
Matsusaki, Toshiyuki Kida, Apirat Laobuthee, Mitsuru Akashi, “Investigation on Thermoresponsive Behavior of Biodegradable Poly(gamma-glutamic
acid)-graft-L-Phenylalanine Ethyl Ester”, J. Polym. Sci. Part A: Polym. Chem., 50, 4823 (2012).

70) Junichi Sasaki, Takuya Matsumoto, Hiroshi Egusa, Michiya Matsusaki,
Akihiro Nishiguchi, Takayoshi Nakano, Mitsuru Akashi, Satoshi Imazato,
Hirofumi Yatani, “In vitro reproduction of endochondral ossification using a 3D mesenchymal
stem cell construct”, Integrat. Biol., 1207 (2012).

69) Paninee Chetprayoon, Koji Kadowaki, Michiya Matsusaki, Mitsuru Akashi,
“Survival and Structural Evaluations of Three-Dimensional Tissues Fabricated by Hierarchical Cell Manipulation Technique”, Acta Biomater., 9, 4698 (2012).

68) Shi Dongjian, Michiya Matsusaki, Chen Mingqing, Mitsuru Akashi, “Effect of Degree of Branching on Properties of Photosensitive Nanoparticles
as Drug-Delivery Carriers”, Macromol. Chem. Phys., 213, 2157 (2012).

67) Yosuke Amemiya, Keiko Kawano, Michiya Matsusaki, Mitsuru Akashi, Noriyuki
Nakamura, Chikashi Nakamura, "Formation of nanofilms on cell surfaced to improve the insertion efficiency
of a nanoneedle into cells", Biochem. Biophys. Res. Commun., 420, 662 (2012).

66) H. Hosoya, K. Kadowaki, M. Matsusaki, H. Cabral, H. Nishihara, H.Ijichi,
K. Koike, K. Kataoka, K. Miyazono, M. Akashi, M. R. Kano, "Engineering Fibrotic Tissue in Pancreatic Cancer: A Novel Three-dimensional
Model to Investigate Nanoparticle Delivery", Biochem.Biophys. Res. Commun., 419, 32-37 (2012).

65) Michiya Matsusaki, Hiroharu Ajiro, Toshiyuki Kida, Takeshi Serizawa,
Mitsuru Akashi, "LbL Assembly Through Weak Interactions and Their Biomedical Applications", Adv.Mater., 24, 454-474 (2012).

64)M. Matsusaki, "Development of Three-Dimensional Tissue Models Based on Hierarchical Cell Manipulation Using Nanofilms". Bull. Chem. Soc. Jpn. 85, 401 (2012). Award Account, Elected as Hot Articles in CSJ Journal Report.

63) Masaaki Omichi, Michiya Matsusaki, Ikuro Maruyama, Mitsuru Akashi,
“Improvement of Blood Compatibility on Polysulfone?Polyvinylpyrrolidone
Blend Films as a ModelMembrane of Dialyzer by Physical Adsorption of Recombinant Soluble Human Thrombomodulin” J. Biomater. Sci.: Polymer Edn. 23, 593-608 (2012).
62) Michiya Matsusaki, Koji Kadowaki, Eijiro Adachi, Takeshi Sakura, Utako
Yokoyama, Yoshihiro Ishikawa, Mitsuru Akashi, "Morphological and Histological Evaluations of 3D-Layerd Blood Vessel Constructs
Prepared by Hierarchical Cell Manipulation", J. Biomater. Sci. Polymer Edn., 23,63-79 (2012).
2011年
61) Michiya Matsusaki, Suzuka Amemori, Koji Kadowaki, and Mitsuru Akashi,
“Quantitative 3D-Analysis of Nitric Oxide Diffusion in a 3D-Artery Model
Using Sensor Particle” Angew. Chem. Int. Ed., 50,7557-7561 (2011).

60) Akihiro Nishiguchi, Hiroaki Yoshida, Michiya Matsusaki, and Mitsuru
Akashi, “Rapid Construction of Three-dimensional Multilayered Tissues with Endothelial
Tube Networks by the Cell-accumulation Technique” Adv. Mater., 23, 3506-3510 (2011).

59) Tran Hang Thi, Michiya Matsusaki, Hiroshi Hirano, Hiroaki Kawano, Yasuyuki
Agari, and Mitsuru Akashi, “Mechanism of High Thermal Stability of Commercial Polyesters and Polyethers
Conjugated with Bio-Based Caffeic Acid” J. Polym. Sci. Polym. Chem., 49, 3152 (2011).

58) Michiya Matsusaki, Ryotaro Amekawa, Masahiro Matsumoto, Yuji Tanaka,
Akira Kubota, Kohji Nishida, Mitsuru Akashi, "Physical and Specific Crosslinking of Collagen Fibers by Supramolecular Nano-gelators" Adv.Mater., 23, 2957-2961 (2011).

57) Yuji Tanaka, Akira Kubota, Michiya Matsusaki, Thomas Duncan, Yoshikiyo
Hatakeyama, Katsuya Fukuyama, Andrew J. Quantock, Masayuki Yamato, Mitsuru
Akashi, Kohji Nishida, “Anisotropic Mechanical Properties of Collagen Hydrogels Induced by Uniaxial-flow for Ocular Applications”, J. Biomater. Sci. Polymer Edn., 22, 1427(2011).
56) Michiya Matsusaki, Masahiro Matsumoto, Tomonori Waku, Mitsuru Akashi,
“Self-Assembled Structure of Peptide Nanospheres Induces High Stability
against Hydrolysis and Sterilization”, J. Biomater. Sci. Polymer Edn., 22, 1035 (2011).
55) Donjian Shi, Michiya Matsusaki and Mitsuru Akashi, “Photo-tunable Protein Release from Biodegradable nanoparticles Composed
of Cinnamic Acid Derivatives”, J. Control. Release 149, 182-189 (2011).

2010年
54) Koji Kadowaki, Michiya Matsusaki, Mitsuru Akashi, "Three-dimensional Constructs Induce High Cellular Activity: Structural Stability and the Specific Production of Proteins and Cytokines", Biochem. Biophys. Res. Commun., 402, 153-157 ( 2010).

53) Masaaki Omichi, Michiya Matsusaki, S. Kato, Ikuro Maruyama, Mitsuru
Akashi, "Enhancement of the Blood Compatibility of Dialyzer Membranes by the Physical
Adsorption of Human Thrombomodulin (ART-123)", J. Biomed. Mater. Res. Part:B, 95B, 291-297 (2010).

52) Akihiro Nishiguchi, Hiroaki Yoshida, Michiya Matsusaki and Mitsuru
Akashi, “Preparation of Reduction-Sensitive Nanogels with a Large Swelling Capacity
by a Surfactant-Free Precipitation Method”, Chem. Lett., 39, 1184-1185 (2010).

51) Tomonori Waku, Masahiro Matsumoto, Michiya Matsusaki, Mitsuru Akashi,
“Complete Surface Control of Peptide Nanospheres with Detachable and Attachable
Polymer Brush Layers”, Chem. Commun., 46, 7025-7027 (2010).

50) Koji Kadowaki, Michiya Matsusaki, Mitsuru Akashi, “Control of Cell Surface and Functions by Layer-by-Layer Nanofilms”, Langmuir, 26, 5670-5678 (2010).

49) Michiya Matsusaki, Masaaki Omichi, Koji Kadowaki, Bong Hoon Kim, Sang
Ouk Kim, Ikuro Maruyama, Mitsuru Akashi, “Protein Nanoarrays on a Highly-Oriented Lamellar Surface”, Chem. Commun., 46, 1911-1913 (2010).

48) Takayuki Imoto, Toshiyuki Kida, Michiya Matsusaki, Mitsuru Akashi,
“Preparation and Unique pH-Responsive Properties of Novel Biodegradable Nanocapsules Composed of Poly(gamma-glutamic acid) and Chitosan as Weak Polyelectrolytes”, Macromol. Biosci., 10, 271-277 (2010).

47) Hiroaki Yoshida, Michiya Matsusaki, Mitsuru Akashi, “Development of Thick and Highly Cell-Incorporated Engineered Tissues by
Hydrogel Template Approach with Basic Fibroblast Growth Factor or Ascorbic
Acid", J. Biomater. Sci. Polymer Edn., 21, 415-428 (2010).
46) Suzuka Amemori, Michiya Matsusaki, Mitsuru Akashi, “Biocompatible and Highly-sensitive Nitric Oxide Sensor Particles Prepared
by Layer-by-layer Assembly”, Chem. Lett., 39, 42-43 (2010).

2009年
45)M. Matsusaki and M. Akashi,"Functional Multilayered Capsules for Targeting and Local Drug Delivery", Expert Opin. Drug Deliv. 6, 1207 (2009).

44) Dongjian Shi, Michiya Matsusaki, Mitsuru Akashi, “Photo-Crosslinking Induces Size Change and Stealth Properties of Water-Dispersible
Cinnamic Acid Derivative Nanoparticles”, Bioconjugate Chem., 20, 1917-1923 (2009).

43) Tran Hang Thi, Michiya Matsusaki, Mitsuru Akashi, “Photoreactive Polylactide Nanoparticles by the Terminal Conjugation of
Bio-based Caffeic Acid”, Langmuir, 25, 10567-10574 (2009).

42) Hiroaki Yoshida, Kristina Klinkhammer, Michiya Matsusaki, Martin Moeller,
Doris Klee, Mitsuru Akashi, “Disulfide-Crosslinked Electrospun Poly(γ-glutamic acid) Non-wovens as Reduction-responsive
Scaffolds”, Macromol. Biosci., 9, 568-574 (2009).

41) Tran Hang Thi, Michiya Matsusaki, Mitsuru Akashi, “Development of Photoreactive Degradable Branched Polyesters with High Thermal
and Mechanical Properties”, Biomacromolecules, 10, 766-772 (2009).

40) Dongjian Shi, Michiya Matsusaki, Mitsuru Akashi, “Unique Size-Change Behavior of Photo-Crosslinked Cinnamic Acid Derivative
Nanoparticles during Hydrolytic Degradation”, Macromol. Biosci., 9, 248-255 (2009).

39) Hiroaki Yoshida, Michiya Matsusaki, Mitsuru Akashi, “Scaffold-Mediated 2D-Cellular Orientations for Construction of 3D-Engineered
Tissues Composed of Oriented Cells and ECM”, Adv. Funct. Mater., 19, 1001-1007 (2009).

38) Michiya Matsusaki, Koji Kadowaki, Kosuke Tateishi, Chikahisa Higuchi,
Wataru Ando, David A. Hart, Yoshinari Tanaka, Yasuhiro Take, Mitsuru Akashi,
Hideki Yoshikawa, Norimasa Nakamura, “Scaffold-Free Tissue Engineered Construct-Hydroxyapatite Composites Generated
by an Alternate Soaking Process: Potential for Repair of Bone Defects”, Tissue Eng., 15, 55-63 (2009).
2008年
37) Tran Hang Thi, Michiya Matsusaki, Mitsuru Akashi, “Thermally Stable and Photoreactive Polylactides by the Terminal Conjugation
of Bio-based Caffeic Acid”, Chem. Commun., 3918-3920 (2008).

36) Tomonori Waku, Michiya Matsusaki, Suwabun Chirachanchai, Mitsuru Akashi,
“One-Step Preparation of Cationic Sugar-Peptide Nanospheres Using The Water-soluble
Chitosan-initiated Polymerization of L-Phenylalanine N-Carboxyanhydride”, Chem. Lett., 37, 1262-1263 (2008).

35) Chizuru Hongo, Michiya Matsusaki, Kohji Nishida, Mitsuru Akashi, “Development of a Collagen Hydrogel with High Mechanical Strength by a Simple
Molecular Orientation Method for Triple-Helix”, Chem. Lett., 37, 1254-1255 (2008).

34) Dongjian Shi, Michiya Matsusaki, Tatsuo Kaneko, Mitsuru Akashi, “Photo-Crosslinking and Cleavage Induced Reversible Size Change of Bio-Based
Nanoparticles”, Macromolecules, 41, 8167-8172 (2008).

33) Yuki Itoh, Michiya Matsusaki, Toshiyuki Kida, Mitsuru Akashi, “Locally Controlled Release of Basic Fibroblast Growth Factor from Multilayered
Capsules”, Biomacromolecules, 9, 2202-2206 (2008).

32) Taka-aki Asoh, Michiya Matsusaki, Tatsuo Kaneko, Mitsuru Akashi, “Fabrication of Temperature-Responsive Bending Hydrogels with a Nanostructured
Gradient”, Adv. Mater., 20, 2080-2083 (2008).

31) Yuki Itoh, Michiya Matsusaki, Toshiyuki Kida, Mitsuru Akashi, “Time-modulated Release of Multiple Proteins from Enzyme-responsive Multilayered
Capsules”, Chem. Lett., 37, 238-239 (2008).

30) Tran Hang Thi, Michiya Matsusaki, Dongjian Shi, Tatsuo Kaneko, Mitsuru
Akashi, “Synthesis and Properties of Coumaric Acid Derivative Homopolymers”, J. Biomater. Sci. Polymer Edn., 19, 75-85 (2008).
29) Michiya Matsusaki, Masaaki Omichi, Ikuro Maruyama, Mitsuru Akashi,
“Physical Adsorption of Human Thrombomodulin (ART-123) onto Polymeric Biomaterials
for Developing An Antithrombogenic Blood-Contacting Material”, J. Biomed. Mater. Res. Part:A, 84A, 1-9 (2008).

2015年以降 After 2015
2007年以前 Before 2007